Unit Price: | USD 13.0000 - 17.0000 / Kilogram |
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Model No.: SNT139
Types of: Herbal Extract
Extraction method: Solvent Extraction
package: Bottle, Can, Drum
Extraction Type: Solvent Extraction
Grade: Food Grade
Sample: Avaliable
Shelf Life: 24 Months
Part: Root and Bark
Appearance: Brown Yellow Fine Powder
Packaging: 10g/Bag,1Kg/bag/25kg/Drum,According to your requirements
Productivity: 914000kg
Brand: Sinuote
Transportation: Ocean,Land,Air,Express,Others
Place of Origin: China
Supply Ability: 285000kg
Certificate: ISO9001 ISO22000 HACCP
HS Code: 2932999099
Port: Shanghai,Tianjin,Guangzhou
Moutan Cortex (MCE) has been used in traditional medicine to remove heat from the blood, promote blood circulation and alleviate blood stasis. This study was conducted to evaluate the effects of MCE on regulatory mechanisms of cytokines and nitric oxide (NO) involved in immunological activity of Raw264.7 cells. Cells were pretreated with methanolic extracts of MCE, and further cultured for an appropriate time after lipopolyssacharide (LPS) addition. During the entire experimental period, 0.1 and 0.3 mg ml−1 of MCE had no cytotoxicity. In these concentrations, MCE inhibited the production of NO and prostaglandin E2 (PGE2), the expression of inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2) and phosphorylated inhibitor of κBα (p-IκBα), and the activation of nuclear factor κB (NF-κB). MCE also reduced the concentration of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6) in the Raw264.7 cells that were activated by LPS. These results demonstrate that MCE has anti-inflammatory effects through the inhibition of iNOS and COX-2 expression by suppressing the phosphorylation of I-κBα and the activation of NF-κB.
Moutan bark extract is Natural Plant Extract,Improve Immunity Plant Extract,Food Additives Powder and Water Soluble Plantain Extract.
Function:
1. Have a calming anticonvulsant effect
2. Protective effect of myocardial ischemia
3. Anti-inflammatory and anti-allergic reactions, inhibit arthritis, allergic inflammation
4. Antibacterial and immunoenhancement
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